Prediction Algorithm for Proteasomal Cleavages

PAProC's location within the MHC class I antigen processing pathway.

Experimental distribution of cuts and fragments, produced by the yeast double mutant in enolase (taken from Nussbaum et al., Cleavage motifs of the yeast 20 S proteasome beta subunits deduced from the digests of enolase 1, Proc. Natl Acad. Sci. USA 95, 12504-12509).
Vertical bars indicate proteasomal cut sites; horizontal bars depict the detected cleavage products.

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Last update: 13.4.2005